Anima Astrologiae or A Guide for Astrologers by William Lilly 1676

The 45th is, To consider if the Infortunes are in angles of the Ascendant, that is, in such signs as are in Square or Opposition to the Ascendant, when they afflict any Planet by Square or Opposition; for then they assist so much the worse, and do more mischief, especially if they be in a stronger place than such afflicted Planet; but if they cast only a Trine or a Sextile, it is lessened and the Impediment mitigated. 46. The 46th is, to see whether the Significator be a Fortune or Infortune, the first naturally signifies good and prosperity, the last naturally evil by its malignity; therefore consider the Planets’ places from the Ascendant where they are; for if a Planet be in his Light, or his Hayz in any of his Dignities, or in a good place from the Ascendant, it signifies good, and if it be a good planet the better.

46.Whether the Significator be a Fortune or Infortune